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BETA-ENDOTHELIAL GROWTH FACTOR
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DeCS
Descriptor
English
:
Endothelial Growth Factors
Descriptor
Spanish
:
Factores de Crecimiento Endotelial
Descriptor
Portuguese
:
Fatores de Crescimento Endotelial
Synonyms
English
:
alpha-Endothelial Growth Factor
beta-Endothelial Growth Factor
Endothelial Cell-Derived Growth Factors
Tree Number:
D12.644.276.390
D12.776.467.390
D23.529.390
Definition
English
:
These
growth
factors are soluble
mitogens
secreted by a variety of organs. The factors are a mixture of two single chain
polypeptides
which have affinity to
heparin
. Their
molecular weight
are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate
endothelial cells
to grow and synthesize DNA. The factors are related to both the basic and acidic
FIBROBLAST GROWTH FACTORS
but have different amino acid sequences.
Indexing Annotation
English
:
do not confuse with EGF; (
EPIDERMAL GROWTH FACTOR
)
Pharmacological Action:
Growth Substances
See Related
English
:
Vascular Endothelial Growth Factor A
History Note
English
:
91
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
28920
Unique Identifier:
D016228
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS